Corticostatin 6 |
corticothyrotropes |
Staphylococcus aureus mprF |
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abbr. CS; called also: anti-ACTH peptides.
A family of arginine-rich cysteine-rich proteins structurally and functionally more or less identical with Defensins from leukocytes (for a related factor see also: RK-1). Some corticostatins possess antimicrobial activities like defensins, but not all defensins possess activities against ACTH (for corticostatin HP-4 see: HNP-4 [human neutrophil peptide-4].
Corticostatins have been isolated from rabbit lung extracts, extracts of peritoneal neutrophils, human neutrophils, rat and guinea pig
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