Astakine 1 |
Astakine 2a |
Nectin-3-alpha |
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Astakine 2, which is related to Astakine 1, has been cloned from a crayfish hemocyte cDNA. Two isoforms that differ only in their 3'-untranslated regions have been identified (Astakine 2a, Astakine 2b). Astakine 2a and Astakine 2b both contain an insert of 13 amino acid residues as compared with crayfish astakine 1. A 13 amino acid insert is found also at the same site in an astakine from shrimp Penaeus monodon.
Recombinant astakine 2 does not induce proliferation of crayfish hematopoietic tissue cells, but a significant increase in total hemocyte
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