Adamtsostatin-18 |
ADAMTS protein family |
EC6.2.1.4 |
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Adamtsostatin-like-4 [(ADAMTSL4(790-809); also: TSRC1(790-809)] is a bioactive fragment (see also: cryptides) derived from the TSRC1 [thrombospondin repeat containing protein 1] gene. Adamtsostatin-like-4 [SPWSQCSVRCGRGQRSRQVR] corresponds to residues 790-809 of ADAMTSL4 (Karagiannis and Poppel, 2008). The primary structure of this peptide is similar to the thrombospondin type 1 domains found in thrombospondin-1, thrombospondin-2, the metalloproteinases ADAMTS1 and ADAMTS8. The peptide functions as an inhibitor of angiogenesis
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