TSG genes |
TSGLIAFPRL/Iamide |
VFHLLGKIIHHVGNFVYGFSHVFamide |
||
This cell line has been established from a human signet ring gastric carcinoma. The cells secrete tumor markers CEA and CA 125. They are not tumorigenic in athymic nude mice. The cells express TGF-alpha and high levels of EGF receptor. Cell growth is inhibited upon EGF withdrawal.
The cells express the retinoic acid receptor beta and gamma. Cell growth is inhibited by all-trans-retinoic acid, leading to an arrest in the G0/G1 phase of the cell cycle.
Cell growth is suppressed also by IFN-alpha and IFN-gamma, causing cell cycle arrest.
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |