Tld |
TLEGTKKGHKLHLDYIG |
non-B-cells |
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This peptide, termed SP6023 by the authors, has been identified by bioinformatics analysis. The sequence is derived from a CKIP-1 [casein kinase 2-interacting protein 1] and has been shown to be a potent inducer of endothelial cell apoptosis in the presence of bFGF and VEGF, causing the release of caspase-3 and caspase-7 (Koshimaki et al, 2012).
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.
See also: Angiogenesis Dictionary
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