TIMP-2 peptide 9 |
TIMP-3 T3-loop6 |
CEL |
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[tissue inhibitor of metalloproteinases-3; TIMP metallopeptidase inhibitor 3; metalloproteinase inhibitor 3]. TIMP-3 is a member of a group of tissue inhibitors of metalloproteinases that inhibit matrix metalloproteinases, which are involved in the degradation of the extracellular matrix (see also: TIMP).
TIMP-3 has been identified independently as mig-5 [mitogen-inducible gene 5].
The gene encoding TIMP-3 has been isolated by Apte et al (1994), Wilde et al (1994), and Silbiger et al, (1994).
TIMP-3 has been shown to be expressed by astrocytes, B-cells, cardiomyocytes, cementoblasts,
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