TFAR-15 |
TF-beta |
Inter-alpha-trypsin inhibitor 107 kDa |
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[TF1 cell apoptosis-related gene-19] The approved gene symbol is PDCD5 (programmed cell death-5).
This gene has been identified Liu et al (1999). TFAR-19 is expressed in a human premyeloid cell line established from a patient with erythroleukemia, TF-1, undergoing apoptosis after the withdrawal of GM-CSF from the culture medium. TFAR-19 encodes a protein of 125 amino acids. TFAR-19 is expressed ubiquitously Its expression is upregulated in tumor cells undergoing apoptosis. Expression of the protein enhances apoptosis triggered by the removal of growth factors or serum from cultured cells.
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