T11 target structure |
T12 |
C1q/TNF-related protein 9B |
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[T11 target structure] This protein is identified by a monoclonal antibody (L180/1) to sheep red blood cells. The antibody completely blocks rosette formation between red blood cells and human or sheep T-lymphocytes (Hünig, 1985). The protein is expressed also on sheep T-cells after cell activation (Hünig, 1986), mature and immature hematopoietic cells, vascular endothelial cells and smooth muscle cells (Hünig et al, 1986).
The protein, which functions as a ligand for CD2 (T11), is identical with LFA-3 (CD58
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