PAT |
patched |
Amelin |
||
A mutation found in certain strains of mice. The mutation is lethal and causes severe anatomical malformations in homozygous animals. Heterozygous animals show anomalies in hair coloration. The molecular defect is caused by a deletion of the PDGFRA gene encoding the alpha subunit of the receptor for PDGF (Orr-Urtreger et al, 1992; Morrison-Graham et al, 1992; Stephenson et al, 1991).
... ... ... ... ... Subscribe to continue reading! ... ...
Content view restricted ! |