G1 phase |
G2 accumulation protein |
Early pregnancy factor |
||
[G2 accumulation protein] The approved gene symbol for this receptor is GPR132 [G-protein-coupled receptor-132]. At least two splice variants exist (Ogawa et al, 2010).
G2A is a G-protein-coupled receptor identified originally by Weng et al (1998) as an anti-proliferative cell cycle regulator expressed predominantly in immature T-cells and B-cells. Overexpression of this receptor blocks cells in G2/M of the cell cycle in NIH 3T3 cells. Retrovirus-mediated overexpression of G2A in bone marrow cells expressing the human leukemogenic tyrosine kinase, BCR-ABL significantly attenuates
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |