FIGAILPAIAGLVHGLINR |
FIGF |
dark-colour-inducing neurohormone |
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This multifunctional peptide with the sequence FLGAILKIGHALAKTVLPMVTNAFKPKQ has been isolated from the skin secretion of the Chaco tree frog, Boana raniceps. Figainin 2 exhibits activity against Gram-negative bacteria, Gram-positive bacteria, arboviruses, Trypanosoma cruzi epimastigotes; it does not show activity against yeasts. Figainin 2 also has anticancer peptide activity and shows antiproliferative activity on cancer cells. The peptide is moderately active on human erythrocytes, and activates the oxidative burst in human neutrophils.
For other proteins/peptides with functions in innate immunity
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