FPR-like-2 |
fps |
Y2/131 |
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[FP regulatory protein; F2-alpha receptor regulatory protein; Prostaglandin F2-alpha receptor regulatory protein] Orlicky et al (1996) have isolated a protein that copurifies with the bovine prostaglandin F2-alpha receptor and cloned the corresponding cDNA. FPRP inhibits binding of prostaglandin F2-alpha to the receptor. Orlicky and Nordeen (1996) have shown that the protein, for which they suggested the name prostaglandin F2 alpha receptor regulatory protein, is a type 1 integral membrane protein containing six extracellular immunoglobulin domains. FPRP associates with the prostaglandin F2α receptor and thereby reduces receptor ligand-binding capacity (Orlicky, 1996).
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