EPF-S1 |
EPG |
fwe3 |
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[EPF-induced suppressor factor-2] The production of this biochemically uncharacterized factor of 55 kDa is induced by EPF (early pregnancy factor). Release of the suppressor factor can be stimulated also by Con A (Rolfe et al, 1988). Production of EPF-S2 is induced by EPF-S1 (Rolfe et al, 1995).
The factor is active in T-cell dependent reactions (rosette inhibition test and adoptive transfer of contact sensitivity), inhibiting the delayed type hypersensitivity reaction in this latter assay (Rolfe et al, 1988). EPF-S2 activity is restricted to a locus (or loci) outside the MHC (Rolfe et al, 1988).
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