Coleoptericins |
colibactin |
hemoglobin-zeta-2 |
||
Name given to the active principle responsible for the antitumor activity observed in terminally ill cancer patients treated with a preparation of heat-inactivated Gram-positive or Gram-negative bacteria.
The study of this phenomenon led to the identification of bacterial lipopolysaccharides as an active component of the toxins.
The active principle ultimately responsible for the antitumor responses is known now as TNF-beta, the synthesis of which is induced by bacterial endotoxins.
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