cHDGF |
ChDI |
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[Chondrosarcoma-derived growth factor] abbr. also CHSA-GF. This factor of approximately 18 kDa was isolated originally from a rat chondrosarcoma. It is mitogenic for murine 3T3 fibroblasts and capillary endothelial cells (Shing et al, 1985). The factor also supports angiogenesis in a chicken chorioallantoic membrane assay.
Ch-DGF is one of several heparin binding growth factors identified in various other tissues and belongs to the cationic class of proteins (as opposed to anionic growth factor proteins (Lobb et al, 1986). Ch-DGF is identical with bFGF. See also: CGF which is most likely identical.
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