CRF(1-41) |
CRF2-11 |
Beta-Defensin-5 |
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[cytokine receptor family 2 member 10] CRF2-10 is a member of the type 2 cytokine receptor family (Kotenko, 2001). CRF2-10 is a soluble secreted binding protein known also as IL22BP [IL22 binding protein]. Functional analysis indicates that CRF2-10 inhibits MHC class I antigen expression mediated by IL22. It also inhibits STAT1 and STAT3 DNA-binding complexes and blocks SOCS3.
The approved gene symbol for this protein is IL22RA2 [interleukin-22 receptor-alpha-2; IL22R-alpha-2].
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