CIPAR-1 |
CIPs |
SKALP |
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[CED3/ICH-1 prodomain homologous E10-like regulator] This protein contains a CARD domain in its N-terminus and a C-terminal region rich in serine and threonine residues. CIPER homodimerises via its CARD domain and interacts with viral E10. Expression of CIPER activates transcription factor NF-kappa-B. The protein does not interact with the apoptosis regulators ARC, RAIDD, RICK, caspase-2, caspase-9, or APAF-1.
The protein has been isolated independently as BCL10, CARMEN, and CLAP.
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