amelocytes |
amelogenin X |
pyroELYAFPRVamide |
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This protein of 28 kDa is encoded and expressed by genes on the Y chromosome (abbr. AMGY, AMELY; amelogenin Y) and the X chromosome (AMGX, AMELX; amelogenin X) (Lau et al, 1989; Salido et al, 1992; Nakahori et al, 1991). The amelogenin sequence is highly conserved throughout evolution (Sire et al, 2005).
In the mouse, the Amelogenin gene appears to be located on the X chromosome only (Chapman et al, 1991). The protein encoded by the X chromosome gene differs from that encoded by the Y chromosome protein by a deletion of a methionine at codon 29 (Catalano-Sherman et al, 1993). Various slice variants of amelogenin have been reported (Bartlett et al, 2006; Gibson et al, 1991; Bonass et al, 1992; Simmer 1995; Veis et al, 2003). The
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