ADAM4 |
ADAM6 |
KIAA0185 |
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[a disintegrin and metalloprotease domain 5; ADAM metallopeptidase domain 5] This protein, which is expressed in mouse testis and is thought to play a role in sperm-egg plasma membrane adhesion and fusion, is a member of the ADAM protein family (Yuan et al, 1997). The protein has been identified independently as tMDC-2. Frayne et al (1999) have identified multiple isoforms of human tMDC-2 transcripts in humana, all of which are also non-functional owing to the presence of deletions and in-frame termination codons
For other entries pertaining to metalloproteinases see also the Metalloproteinase Dictionary section of this encyclopedia.
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